Description

5-Chlorouracil is a halogenated pyrimidine derivative, a crucial building block in organic synthesis and pharmaceutical research. Its primary value lies in its role as a key intermediate for the synthesis of more complex nucleoside analogs and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of antiviral and anticancer nucleoside drugs.
• Agrochemical Research: Used in developing novel herbicides and plant growth regulators based on pyrimidine chemistry.
• Biochemical Tool: Serves as a modified base in oligonucleotide synthesis for genetic research and diagnostic probe development.
• Organic Synthesis: Acts as a versatile building block for creating heterocyclic compounds and complex molecular architectures.
• Academic & Industrial R&D: Fundamental material for studying enzyme inhibition, metabolic pathways, and structure-activity relationships (SAR).

Basic Information

Product Name	5-Chlorouracil
CAS No.	1820-81-1
Molecular Formula	C4H3ClN2O2
Molecular Weight	146.53 g/mol
Synonyms	5-Chloro-2,4(1H,3H)-pyrimidinedione; 5-Chloro-1H-pyrimidine-2,4-dione; 5-Chloropyrimidine-2,4-diol; 2,4-Dihydroxy-5-chloropyrimidine; NSC 38280; 5-Cl-Ura
EINECS	217-345-6

Quality Control

Our 5-Chlorouracil is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with products typically meeting specifications suitable for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for every batch upon request, supporting your compliance and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	~300°C (dec.)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.