Description

6-Chlorouracil is a halogenated pyrimidine derivative, a crucial heterocyclic building block in organic synthesis and pharmaceutical research. Its unique structure, featuring a chlorine atom at the 6-position, makes it a versatile intermediate for developing nucleoside analogs and other bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral and anticancer nucleoside analogs, such as certain fluorouracil derivatives.
• Agrochemical Research: Serves as a building block for developing novel herbicides and plant growth regulators that target pyrimidine metabolism.
• Biochemical Research: Used in studies of enzyme inhibition, nucleic acid chemistry, and metabolic pathway analysis.
• Fine Chemical Synthesis: An important starting material for synthesizing more complex heterocyclic compounds and specialty chemicals.
• Academic & R&D Laboratories: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	6-Chlorouracil
CAS No.	4270-27-3
Molecular Formula	C4H3ClN2O2
Molecular Weight	146.53 g/mol
Synonyms	6-Chloro-2,4(1H,3H)-pyrimidinedione; 6-Chloro-1H-pyrimidine-2,4-dione; 6-Chloropyrimidine-2,4(1H,3H)-dione; 2,4-Dihydroxy-6-chloropyrimidine; 6-Chloro-uracil; NSC 38297
EINECS	224-254-1

Quality Control

Our 6-Chlorouracil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	~300 °C (dec.)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.