Description

2-Aminopyrimidine CAS NO 109-12-6 is a versatile heterocyclic aromatic amine that serves as a critical building block in organic synthesis. Its pyrimidine core with an amino substituent makes it a valuable intermediate for constructing complex molecules with pharmaceutical and agrochemical activity. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the pyrimidine ring is a core structural motif.
• Chemical Research & Development: Serves as a fundamental reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Employed in the development of organic ligands for metal-organic frameworks (MOFs) and other functional materials.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of certain specialized dyes and colorants.

Basic Information

Product Name	2-Aminopyrimidine
CAS No.	109-12-6
Molecular Formula	C4H5N3
Molecular Weight	95.10 g/mol
Synonyms	Pyrimidin-2-amine; 2-Pyrimidinamine; 2-Pyrimidylamine; α-Aminopyrimidine; 2-AP; Aminopyrimidine; 2-Amino-1,3-diazine
EINECS	203-648-4

Quality Control

Our 2-Aminopyrimidine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We can supply material compliant with various pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The product is hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	125 - 128 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.