Description

4-Chloro-2,6-Diaminopyrimidine is a versatile halogenated pyrimidine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both chloro and amino substituents, makes it a valuable building block for constructing complex heterocyclic systems and active pharmaceutical ingredients. This high-purity compound is essential for research and development laboratories, pharmaceutical manufacturers, and agrochemical companies engaged in the synthesis of novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Used in nucleophilic substitution and cross-coupling reactions to introduce the pyrimidine core into more complex molecular architectures.
• Material Science Research: Intermediate for creating specialized polymers, ligands for metal-organic frameworks (MOFs), and other advanced functional materials.
• Dye and Pigment Manufacturing: Serves as a starting material for certain heterocyclic dyes and colorants.
• Biochemical Research: Used in studies involving nucleic acid analogs and enzyme inhibition mechanisms.

Basic Information

Product Name	4-Chloro-2,6-Diaminopyrimidine
CAS No.	156-83-2
Molecular Formula	C4H5ClN4
Molecular Weight	144.56 g/mol
Synonyms	2,6-Diamino-4-chloropyrimidine; 4-Chloro-2,6-pyrimidinediamine; 4-Chloro-2,6-diamino-pyrimidine; NSC 403697; 4-Chloro-2,6-diaminopyrimidine; 4-Chloro-2,6-diamino-1H-pyrimidine; 4-Chloro-2,6-diamino-1H-pyrimidin-1-one (tautomer); 156-83-2
EINECS	205-860-8

Quality Control

Our 4-Chloro-2,6-Diaminopyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.