Description

(2,4-Diaminopteridin-6-Yl)Methanol Hydrochloride Hydrate is a high-purity chemical building block and intermediate of significant interest in advanced organic synthesis. Its core value lies in its functionalized pteridine scaffold, which is a privileged structure in medicinal chemistry and materials science. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for applications in oncology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of pteridine-based drug candidates, including potential kinase inhibitors and antifolate agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving folate-dependent pathways.
• Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds for high-value material and agrochemical research.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	(2,4-Diaminopteridin-6-Yl)Methanol Hydrochloride Hydrate
CAS No.	73978-41-3
Molecular Formula	C7H11ClN6O2 (anhydrous hydrochloride) / C7H9N6O • HCl • xH2O
Molecular Weight	246.66 g/mol (anhydrous hydrochloride)
Synonyms	6-(Hydroxymethyl)-2,4-pteridinediamine hydrochloride hydrate; 2,4-Diamino-6-(hydroxymethyl)pteridine hydrochloride hydrate; 6-(Hydroxymethyl)-2,4-diaminopteridine HCl hydrate; (2,4-Diamino-6-pteridinyl)methanol hydrochloride hydrate; Pteridine-6-methanol, 2,4-diamino-, hydrochloride, hydrate
EINECS	Contact for details

Quality Control

Our (2,4-Diaminopteridin-6-Yl)Methanol Hydrochloride Hydrate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.