Description

1-Piperazinecarboxylic acid, 4-[7-(8-chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-(methylsulfinyl)pyrido[3,4-d]pyrimidin-4-yl]-2-(cyanomethyl)-, phenylmethyl ester, (2S)- is a sophisticated chiral organic compound featuring a complex, multi-cyclic structure. This high-value intermediate is critical for pharmaceutical research and development, particularly in the synthesis of targeted small molecule therapeutics. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on novel drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential active pharmaceutical ingredients (APIs), especially for kinase inhibitors or other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with specific biological activity.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale, focusing on yield optimization and impurity profile control.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in API manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for client drug discovery programs.

Basic Information

Product Name	1-Piperazinecarboxylic acid, 4-[7-(8-chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-(methylsulfinyl)pyrido[3,4-d]pyrimidin-4-yl]-2-(cyanomethyl)-, phenylmethyl ester, (2S)-
CAS No.	2502155-77-1
Molecular Formula	C32H29ClN6O3S
Molecular Weight	613.13 g/mol
Synonyms	(2S)-Benzyl 2-(cyanomethyl)-4-[7-(8-chloronaphthalen-1-yl)-5,6,7,8-tetrahydro-2-(methylsulfinyl)pyrido[3,4-d]pyrimidin-4-yl]piperazine-1-carboxylate; (S)-Benzyl 2-(cyanomethyl)-4-(7-(8-chloro-1-naphthyl)-5,6,7,8-tetrahydro-2-(methylsulfinyl)pyrido[3,4-d]pyrimidin-4-yl)piperazine-1-carboxylate; UNII-9J8T9Q3U4C; 9J8T9Q3U4C; Benzyl (2S)-2-(cyanomethyl)-4-[7-(8-chloro-1-naphthyl)-5,6,7,8-tetrahydro-2-(methylsulfinyl)pyrido[3,4-d]pyrimidin-4-yl]piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to confirm identity, chiral purity, and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters including assay, enantiomeric excess, and impurity profiles to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C in a dry environment. The compound is moisture-sensitive; allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.