Description

Ethanol, 2-[[(3aR,4S,6R,6aS)-6-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]nitrosoamino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]- is a high-purity, complex synthetic intermediate of significant importance in modern pharmaceutical research and development. This compound is specifically designed as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting complex disease pathways. It is an essential material for medicinal chemists and process development scientists in pharmaceutical, biotechnology, and advanced fine chemical sectors requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Process Chemistry Development: Serves as a standard or starting material for scaling up and optimizing API manufacturing routes.
• Bioconjugation & Prodrug Synthesis: Potential use in creating advanced drug delivery systems due to its functionalized ethanol moiety.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in organic and medicinal chemistry.

Basic Information

Product Name	Ethanol, 2-[[(3aR,4S,6R,6aS)-6-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]nitrosoamino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-
CAS No.	2476859-56-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-[[(3aR,4S,6R,6aS)-6-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]nitrosoamino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol; Advanced Pharmaceutical Intermediate 2476859-56-8; Complex Triazolopyrimidine Derivative; Nitrosoamino Cyclopropane Intermediate; Difluorophenyl Cyclopropyl Triazolopyrimidine Ethanol; (3aR,4S,6R,6aS)-Isomer of specified ethanol derivative; Propylthio Triazolopyrimidine Building Block
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality control protocols in facilities adhering to cGMP principles. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and LC-MS to confirm identity, isomeric purity, and chemical integrity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below for long-term stability. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Store in a dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Isomeric Purity (Chiral HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.