Description

D-Lysine, L-alanyl-L-cysteinyl-L-α-aspartyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-cysteinylglycylglycyl-D-lysyl-D-leucyl-L-alanyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-, cyclic (2→10),(4→8)-bis(disulfide) is a complex, synthetic cyclic peptide featuring a unique bis-disulfide bridge structure. This engineered molecular architecture is critical for conferring enhanced stability and specific biological activity, making it a valuable building block for advanced research and development. It is primarily sought by pharmaceutical R&D teams and biotechnology companies focused on peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Pharmaceutical Research & Development: As a key intermediate or active pharmaceutical ingredient (API) in the development of novel peptide-based drugs targeting specific receptors or enzymes.
• Bioconjugation & Probe Development: Utilized for creating labeled peptides for diagnostic assays, imaging agents, or targeted drug delivery systems due to its modifiable structure.
• Biochemical Research: Serves as a high-purity reference standard or substrate in enzymatic studies, receptor binding assays, and structure-activity relationship (SAR) investigations.
• Preclinical Studies: Used in in vitro and in vivo models to evaluate pharmacokinetics, efficacy, and toxicity of new therapeutic candidates.
• Peptide Library Synthesis: A specialized component in the construction of diverse peptide libraries for high-throughput screening in drug discovery.

Basic Information

Item	Details
Product Name	D-Lysine, L-alanyl-L-cysteinyl-L-α-aspartyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-cysteinylglycylglycyl-D-lysyl-D-leucyl-L-alanyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-, cyclic (2→10),(4→8)-bis(disulfide)
CAS No.	2243207-09-0
Molecular Formula	C108H174N34O28S4
Molecular Weight	Contact for details
Synonyms	Cyclic (2-10),(4-8)-bis(disulfide) peptide; Custom cyclic bis-disulfide peptide; CAS 2243207-09-0; Synthetic constrained peptide; Engineered disulfide-bridged peptide; Research-grade cyclic peptide; Pharmaceutical peptide intermediate; [D-Lys1, Cys2, Cys4, Cys8, Cys10]-cyclic peptide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, LC-MS, and NMR to confirm identity, purity, and structural integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Production can adhere to GMP guidelines for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.