Description

5H-1,3-Dioxolo4,5-cpyrrole-5-carboxylic acid, 4-2-bis(4-methoxyphenyl)methylamino-4-(phenylmethoxy)-5-(phenylmethoxy)methyl-5H-pyrrolo3,2-dpyrimidin-7-yl-6-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-, 1,1-dimethylethyl ester, (3aS,4S is a highly specialized, complex organic intermediate featuring a unique pyrrolopyrimidine core structure. This compound is of significant value for its role as a key building block in advanced synthetic chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the synthesis of complex heterocyclic molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: Critical building block in the multi-step synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Process Chemistry: Serves as a key intermediate in the scale-up and optimization of synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals for advanced material science and agrochemical research.

Basic Information

Product Name	5H-1,3-Dioxolo4,5-cpyrrole-5-carboxylic acid, 4-2-bis(4-methoxyphenyl)methylamino-4-(phenylmethoxy)-5-(phenylmethoxy)methyl-5H-pyrrolo3,2-dpyrimidin-7-yl-6-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-, 1,1-dimethylethyl ester, (3aS,4S
CAS No.	299917-28-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	tert-Butyl (3aS,4S)-4-({4-[bis(4-methoxyphenyl)methylamino]-5-[(benzyloxy)methyl]-7-{[6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2,2-dimethyltetrahydro-5H-[1,3]dioxolo[4,5-c]pyrrol-5-yl]carbonyl}-5H-pyrrolo[3,2-d]pyrimidin-2-yl}oxy)benzyl carbonate; (3aS,4S)-tert-Butyl 4-((4-(bis(4-methoxyphenyl)amino)-5-((benzyloxy)methyl)-7-((6-((tert-butyldimethylsilyloxy)methyl)-2,2-dimethyltetrahydro-5H-[1,3]dioxolo[4,5-c]pyrrol-5-yl)carbonyl)-5H-pyrrolo[3,2-d]pyrimidin-2-yl)oxy)benzyl carbonate; CAS 299917-28-5; Advanced Pyrrolopyrimidine Intermediate; Complex Heterocyclic Ester Intermediate; Pharma Building Block 299917-28-5
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to stringent quality protocols. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry to confirm identity and purity. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development specifications. Quality systems are designed to support GMP-grade manufacturing requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.