Description

L-Cysteine, L-cysteinylglycyl-L-glutaminyl-L-arginyl-L-α-glutamyl-L-threonyl-L-prolyl-L-α-glutamylglycyl-L-alanyl-L-α-glutamyl-L-alanyl-L-lysyl-L-prolyl-L-tryptophyl-L-tyrosyl-, cyclic (1→17)-disulfide is a complex, synthetic cyclic peptide with a defined disulfide bridge, representing a high-purity, research-grade biochemical. This compound is critical for advanced scientific investigations, particularly in structural biology and peptide-based drug discovery, due to its specific conformational constraints. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focusing on peptide chemistry, receptor-ligand interactions, and novel therapeutic agent development.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the discovery and development of novel peptide-based therapeutics and diagnostic agents.
• Biochemical Research: Used as a model compound in studies of protein folding, disulfide bond formation, and peptide stability under various conditions.
• Receptor Binding Studies: Employed in competitive binding assays and structure-activity relationship (SAR) studies to understand biological pathways and identify potential drug targets.
• Academic & Institutional Research: A vital tool for universities and research institutes conducting fundamental research in organic chemistry, medicinal chemistry, and molecular biology.
• Reference Standard: Acts as a high-purity calibrant or standard for analytical methods such as HPLC, LC-MS, and NMR in quality control laboratories.

Basic Information

Item	Details
Product Name	L-Cysteine, L-cysteinylglycyl-L-glutaminyl-L-arginyl-L-α-glutamyl-L-threonyl-L-prolyl-L-α-glutamylglycyl-L-alanyl-L-α-glutamyl-L-alanyl-L-lysyl-L-prolyl-L-tryptophyl-L-tyrosyl-, cyclic (1→17)-disulfide
CAS No.	259206-53-6
Molecular Formula	C86H124N24O25S2
Molecular Weight	1918.2 g/mol
Synonyms	Cyclo(L-Cys-Gly-Gln-Arg-Glu-Thr-Pro-Glu-Gly-Ala-Glu-Ala-Lys-Pro-Trp-Tyr); Cyclic CGRGETPEGAEAAKPWY (1→17)-disulfide; CGRGETPEGAEAAKPWY cyclic peptide; H-Cys-Gly-Gln-Arg-Glu-Thr-Pro-Glu-Gly-Ala-Glu-Ala-Lys-Pro-Trp-Tyr-OH (cyclic 1-17 disulfide); [Cyclo(1-17)]CGRGETPEGAEAAKPWY; Synthetic CGRGETPEGAEAAKPWY cyclic peptide; CAS 259206-53-6
EINECS	Contact for details

Quality Control

Our L-Cysteine, L-cysteinylglycyl-L-glutaminyl-L-arginyl-L-α-glutamyl-L-threonyl-L-prolyl-L-α-glutamylglycyl-L-alanyl-L-α-glutamyl-L-alanyl-L-lysyl-L-prolyl-L-tryptophyl-L-tyrosyl-, cyclic (1→17)-disulfide is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. All products undergo rigorous analytical testing, including HPLC, MS, and NMR, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For extended storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.