Description

1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-4-(benzoylamino)(methylthio)methyleneamino-5-(ethoxycarbonyl)-1H-pyrrol-3-yltetrahydro-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8R,9aS)- is a sophisticated, high-purity heterocyclic compound featuring a complex fused-ring structure with silicon and oxygen. This advanced chemical intermediate is valued for its unique molecular architecture, which provides a versatile scaffold for the synthesis of novel materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules with specific stereochemical and functional properties.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the creation of novel, high-performance pesticides and herbicides, leveraging its complex structure for targeted biological activity.
• Advanced Material Precursor: Serves as a specialized monomer or cross-linking agent in the development of performance polymers, resins, and silicon-based hybrid materials.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D to explore new synthetic methodologies, asymmetric catalysis, and reaction mechanisms.
• Ligand & Chelating Agent Development: Its structure makes it a candidate for designing novel ligands for metal complexes used in catalysis or imaging.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific, high-value compounds.

Basic Information

Product Name	1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-4-(benzoylamino)(methylthio)methyleneamino-5-(ethoxycarbonyl)-1H-pyrrol-3-yltetrahydro-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8R,9aS)-
CAS No.	222854-88-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	tert-Butyl (6aR,8R,9aS)-8-[4-[[(benzoylamino)(methylthio)methylene]amino]-5-(ethoxycarbonyl)-1H-pyrrol-3-yl]tetrahydro-2,2,4,4-tetraisopropyl-1,3,5,2,4-trioxadisilocino[7,6-b]pyrrole-7(6H)-carboxylate; (6aR,8R,9aS)-tert-Butyl 8-(4-((benzamido(methylthio)methylene)amino)-5-(ethoxycarbonyl)-1H-pyrrol-3-yl)tetrahydro-2,2,4,4-tetraisopropyl-1,3,5,2,4-trioxadisilocino[7,6-b]pyrrole-7(6H)-carboxylate; CAS 222854-88-8; Advanced Siloxane-Pyrrole Hybrid Intermediate; Chiral Trioxadisilocino Pyrrole Ester
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, chiral purity, and chemical composition. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development projects with custom purity grades and can align with cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.