Description

1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-1-cyano-2-(2-ethoxy-2-oxoethyl)aminoethenyltetrahydro-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8R,9aS)- is a high-purity, complex heterocyclic compound featuring a unique silicon-oxygen framework integrated with a pyrrole-carboxylic acid ester structure. This advanced chemical intermediate is valued for its precise stereochemistry and functional group diversity, enabling sophisticated molecular construction in specialized synthesis. It is primarily sought by R&D and process development teams in the pharmaceutical and advanced materials sectors for applications in novel drug discovery and high-performance polymer development.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research.
• Advanced Organic Synthesis: Used in complex multi-step syntheses to introduce specific stereocenters and functional groups, such as cyano and ester moieties.
• Materials Science Research: Serves as a precursor for developing novel silicon-containing polymers or hybrid organic-inorganic materials with tailored properties.
• Ligand and Catalyst Development: Potential utility in creating novel chelating ligands or organocatalysts due to its multifunctional and sterically hindered architecture.
• Agrochemical Research: Investigated as an intermediate for next-generation crop protection agents requiring complex molecular scaffolds.

Basic Information

Product Name	1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-1-cyano-2-(2-ethoxy-2-oxoethyl)aminoethenyltetrahydro-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8R,9aS)-
CAS No.	222854-85-5
Molecular Formula	C31H51N3O7Si2
Molecular Weight	633.93 g/mol
Synonyms	tert-Butyl (6aR,8R,9aS)-8-((Z)-2-((2-ethoxy-2-oxoethyl)amino)-2-cyanovinyl)tetrahydro-2,2,4,4-tetraisopropyl-1,3,5,2,4-trioxadisilocino[7,6-b]pyrrole-7(6H)-carboxylate; (6aR,8R,9aS)-1,1-Dimethylethyl 8-[(1Z)-1-cyano-2-[(2-ethoxy-2-oxoethyl)amino]ethenyl]tetrahydro-2,2,4,4-tetrakis(1-methylethyl)-1,3,5,2,4-trioxadisilocino[7,6-b]pyrrole-7(6H)-carboxylate; 222854-85-5; Advanced Silicon-Pyrrole Hybrid Intermediate; Chiral Trioxadisilocino Pyrrole Ester
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider the use of desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.