Description

2-Methylpropenoic acid [(1aR,4Z,5aR,8aR,9S,10aR,11R)-1a,2,5a,7,8,8a,9,10-octahydro-11-hydroxy-8-methylene-7-oxo-3H-4,10a-(methanoxymethano)oxireno[5,6]cyclodeca[1,2-b]furan-9-yl] ester is a specialized, high-value chemical intermediate with a complex diterpenoid-derived structure. This compound is critical for advanced organic synthesis, particularly in the development of novel bioactive molecules and complex natural product analogs. It is primarily sought after by research institutions and pharmaceutical development teams working on new therapeutic agents, agrochemicals, and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates and complex active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new pesticides, herbicides, and plant growth regulators with unique modes of action.
• Natural Product Synthesis: A crucial precursor for the semi-synthesis or total synthesis of complex diterpenoid natural products and their derivatives.
• Biochemical Research: Employed in the study of enzyme inhibitors, receptor ligands, and other biologically active compounds.
• Fine Chemical Manufacturing: Utilized in the production of specialty chemicals, flavors, and fragrances requiring sophisticated chiral intermediates.
• Academic & Industrial R&D: Essential for exploratory chemistry and process development in both university laboratories and corporate R&D centers.

Basic Information

Item	Details
Product Name	2-Methylpropenoic acid [(1aR,4Z,5aR,8aR,9S,10aR,11R)-1a,2,5a,7,8,8a,9,10-octahydro-11-hydroxy-8-methylene-7-oxo-3H-4,10a-(methanoxymethano)oxireno[5,6]cyclodeca[1,2-b]furan-9-yl] ester
CAS No.	27428-86-0
Molecular Formula	C22H26O7
Molecular Weight	402.44 g/mol
Synonyms	Methacrylic acid, (1aR,4Z,5aR,8aR,9S,10aR,11R)-1a,2,5a,7,8,8a,9,10-octahydro-11-hydroxy-8-methylene-7-oxo-3H-4,10a-(methanoxymethano)oxireno[5,6]cyclodeca[1,2-b]furan-9-yl ester; Gibberellin A4 Methacrylate; GA4 Methacrylate; (1aR,4Z,5aR,8aR,9S,10aR,11R)-9-[(2-Methyl-1-oxo-2-propen-1-yl)oxy]-1a,2,5a,7,8,8a,9,10-octahydro-11-hydroxy-8-methylene-7-oxo-3H-4,10a-(methanoxymethano)oxireno[5,6]cyclodeca[1,2-b]furan; Gibberellin derivative ester
EINECS	Contact for details

Quality Control

Our 2-Methylpropenoic acid [(1aR,4Z,5aR,8aR,9S,10aR,11R)-1a,2,5a,7,8,8a,9,10-octahydro-11-hydroxy-8-methylene-7-oxo-3H-4,10a-(methanoxymethano)oxireno[5,6]cyclodeca[1,2-b]furan-9-yl] ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.