Description

(4R)-4-[[(3S,6R,9S,12R,15S,18R,21R,22R)-3-[(2S)-butan-2-yl]-6,12-bis(hydroxymethyl)-22-methyl-9,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-18-propan-2-yl-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]carbamoyl]-4-[[(2S)-2-[[(3R)-3-hydroxydecanoyl]amino]-4-methyl-pentanoyl]amino]butanoic acid is a complex, high-purity cyclic peptide derivative of significant interest in advanced pharmaceutical research and development. Its intricate molecular architecture makes it a valuable intermediate or reference standard for creating novel therapeutic agents, particularly in the fields of oncology and immunology. This compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on peptide-based drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel peptide-based drug candidates.
• Research & Development: Used as a reference standard or lead compound in biochemical and pharmacological studies targeting specific receptors or enzymes.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex peptide molecules.
• Bioconjugation: Its functional groups allow for site-specific conjugation to other molecules, such as antibodies or polymers, for creating targeted therapies.
• Academic Research: Utilized in university and institutional labs for studying peptide structure-activity relationships (SAR) and molecular recognition.

Basic Information

Product Name	(4R)-4-[[(3S,6R,9S,12R,15S,18R,21R,22R)-3-[(2S)-butan-2-yl]-6,12-bis(hydroxymethyl)-22-methyl-9,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-18-propan-2-yl-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]carbamoyl]-4-[[(2S)-2-[[(3R)-3-hydroxydecanoyl]amino]-4-methyl-pentanoyl]amino]butanoic acid
CAS No.	27127-62-4
Molecular Formula	C58H96N8O15
Molecular Weight	1145.4 g/mol
Synonyms	Cyclic Peptide Derivative 27127-62-4; Depsipeptide Analog; 3-Hydroxydecanoyl-containing Cyclic Peptide; Macrocyclic Peptide Ester; Lipopeptide Derivative; (All-S,R)-configured Cyclic Hexapeptide Lactone Derivative; 4-[[(3S,6R,9S,12R,15S,18R,21R,22R)-3-sec-Butyl-6,12-bis(hydroxymethyl)-22-methyl-9,15-diisobutyl-2,5,8,11,14,17,20-heptaoxo-18-isopropyl-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]carbamoyl]-4-[[(2S)-2-[[(3R)-3-hydroxydecanoyl]amino]-4-methylpentanoyl]amino]butanoic Acid
EINECS	Contact for details

Quality Control

Our (4R)-4-[[(3S,6R,9S,12R,15S,18R,21R,22R)-3-[(2S)-butan-2-yl]-6,12-bis(hydroxymethyl)-22-methyl-9,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-18-propan-2-yl-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]carbamoyl]-4-[[(2S)-2-[[(3R)-3-hydroxydecanoyl]amino]-4-methyl-pentanoyl]amino]butanoic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Single Unknown Impurity	≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.