Description

(3S)-3-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-4-methylsulfanyl-butanoyl] amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanyl -butanoyl]amino]-3-[[(1S)-1-carbamoyl-2-phenyl-ethyl]carbamoyl]propano ic acid is a complex, high-purity peptide derivative of significant interest in advanced pharmaceutical research and development. Its intricate structure, featuring methionine-like residues and an indole moiety, makes it a valuable building block for novel therapeutic peptides and biochemical probes. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, peptide synthesis, and metabolic studies. Supplied to exacting standards, it is essential for projects requiring precise molecular architecture and reliable chemical performance.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the solid-phase or solution-phase synthesis of complex therapeutic peptides targeting various disease pathways.
• Biochemical Research: Used as a standard or reference compound in studies of peptide structure-activity relationships (SAR), folding, and receptor-ligand interactions.
• Proteomics & Metabolic Studies: Employed in the development of specialized probes or inhibitors for investigating enzymatic processes and metabolic pathways involving sulfur-containing amino acids.
• High-Value API Synthesis: Acts as a key precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) with specific chiral and functional group requirements.
• Academic Research: Utilized in university and institutional labs for advanced organic chemistry and medicinal chemistry projects focusing on peptide mimetics.

Basic Information

Item	Detail
Product Name	(3S)-3-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-4-methylsulfanyl-butanoyl] amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanyl -butanoyl]amino]-3-[[(1S)-1-carbamoyl-2-phenyl-ethyl]carbamoyl]propanoic acid
CAS No.	21163-42-8
Molecular Formula	C36H47N7O8S2
Molecular Weight	769.93 g/mol
Synonyms	H-Met-Gly-Trp-Met-Asn-OH; Methionylglycyltryptophylmethionylasparagine; L-Methionyl-glycyl-L-tryptophyl-L-methionyl-L-asparagine; Peptide sequence: Met-Gly-Trp-Met-Asn; MGWMN; 21163-42-8; (S)-2-((S)-2-((S)-2-(2-((S)-2-Amino-4-(methylthio)butanamido)acetamido)-3-(1H-indol-3-yl)propanamido)-4-(methylthio)butanamido)-3-((S)-1-carbamoyl-2-phenylethylcarbamoyl)propanoic acid
EINECS	Contact for details

Quality Control

Our (3S)-3-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-4-methylsulfanyl-butanoyl] amino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanyl -butanoyl]amino]-3-[[(1S)-1-carbamoyl-2-phenyl-ethyl]carbamoyl]propanoic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical parameters to support your research and regulatory needs. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.