Description

L-Cysteine, L-tyrosyl-L-threonyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-α-glutamyl-L-leucyl-L-cysteinyl-L-isoleucyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-, cyclic (5→13),(8→16)-bis(disulfide) is a complex, cyclic peptide featuring a unique bis(disulfide) bridge structure. This sophisticated molecular architecture is critical for its biological activity and stability, making it a valuable advanced intermediate for pharmaceutical research and development. It is primarily utilized by biotech and pharmaceutical companies engaged in the discovery and synthesis of novel peptide-based therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex peptide drugs targeting specific biological pathways.
• Research & Development: Used in academic and industrial R&D for studying disulfide bond formation, peptide folding, and structure-activity relationships (SAR).
• Bioconjugation: Acts as a precursor for creating peptide-drug conjugates or labeled peptides for diagnostic imaging.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in peptide manufacturing.
• Enzyme Inhibitor Studies: Investigated for potential use in developing inhibitors for specific proteases or enzymes due to its constrained cyclic structure.

Basic Information

Product Name	L-Cysteine, L-tyrosyl-L-threonyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-α-glutamyl-L-leucyl-L-cysteinyl-L-isoleucyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-, cyclic (5→13),(8→16)-bis(disulfide)
CAS No.	1926163-29-2
Molecular Formula	C71H108N18O27S4
Molecular Weight	1749.98 g/mol
Synonyms	Cyclic (Cys-Tyr-Thr-Asp-Glu-Cys-Glu-Leu-Cys-Ile-Asn-Val-Ala-Cys-Thr-Gly) bis(disulfide); Cyclic Peptide with (5-13),(8-16)-bis(disulfide) Bridge; [Cys1, Cys6, Cys9, Cys14]-Peptide; TATDECDECINVACTG Cyclic Bis(disulfide); Custom Cyclic Peptide 1926163-29-2; Research Peptide 1926163-29-2; Advanced Peptide Intermediate
EINECS	Contact for details

Quality Control

Our cGMP-compliant manufacturing ensures this advanced peptide intermediate meets the stringent requirements of pharmaceutical development. Every batch undergoes comprehensive analytical characterization using HPLC, MS, and NMR to confirm identity, purity, and correct disulfide bond formation. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.