Description

Glycinamide, N-(2-mercaptoacetyl)-L-phenylalanyl-N-methyl-L-alanyl-L-asparaginyl-L-prolyl-L-histidyl-L-leucyl-L-seryl-L-tryptophyl-L-seryl-L-tryptophyl-N-methyl-L-norleucyl-N-methyl-L-norleucyl-L-arginyl-L-cysteinyl-, cyclic (1→14)-thioether is a complex, synthetic peptide featuring a critical cyclic thioether bridge, which confers structural stability and specific biological activity. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a highly selective receptor ligand or enzyme modulator. It is primarily utilized by biopharmaceutical companies and research institutions engaged in the discovery of novel therapeutics for metabolic, oncological, and endocrine disorders.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of novel peptide-based therapeutics.
• Drug Discovery Programs: Used in high-throughput screening (HTS) and structure-activity relationship (SAR) studies to identify and optimize new drug candidates.
• Biochemical Research: Employed as a tool compound to study specific biological pathways, receptor binding mechanisms, and enzyme inhibition.
• Preclinical Studies: Utilized in in vitro and in vivo models to evaluate pharmacokinetics, efficacy, and safety profiles.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale synthesis of clinical trial materials.
• Diagnostic Reagent Development: Potential use in the development of specialized assays and diagnostic kits targeting specific biomarkers.

Basic Information

Item	Detail
Product Name	Glycinamide, N-(2-mercaptoacetyl)-L-phenylalanyl-N-methyl-L-alanyl-L-asparaginyl-L-prolyl-L-histidyl-L-leucyl-L-seryl-L-tryptophyl-L-seryl-L-tryptophyl-N-methyl-L-norleucyl-N-methyl-L-norleucyl-L-arginyl-L-cysteinyl-, cyclic (1→14)-thioether
CAS No.	1629655-80-6
Molecular Formula	C94H134N26O22S2
Molecular Weight	Contact for details
Synonyms	Cyclic (1→14)-thioether peptide; GLP-1/GIP/Glucagon tri-agonist analog intermediate; Tirzepatide-related peptide fragment; SAR439152 related compound; LY3298176 analog; Multi-agonist peptide; Glucose-dependent insulinotropic polypeptide (GIP) receptor agonist analog; Glucagon-like peptide-1 (GLP-1) receptor agonist analog
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical use. All batches are characterized and released against stringent specifications, including identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing results from HPLC, MS, and NMR analyses are available upon request. We adhere to a quality management system suitable for supplying materials for non-clinical and clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	≤ 10.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.