Description

3,5a-Epoxy-2H,5aH,7H-[1,4]dioxepino[2,3-e]oxepino[2,3-d]pyrazino[1,2-a]pyrimidin-8(9H)-one, 3,4-dihydro-4,4-dimethyl-10-(1-methylethyl)-7-(phenylmethyl)-, (3R,5aS,7S,16aR)- is a high-purity, complex heterocyclic compound with a defined stereochemistry. This compound serves as a critical advanced pharmaceutical intermediate or research chemical for the development of novel therapeutic agents. It is essential for R&D and production teams in the pharmaceutical and biotechnology sectors focused on innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold or precursor in drug discovery for developing new compounds with potential biological activity.
• Process Chemistry Development: Serves as a standard or reference material for optimizing synthetic routes and scaling up production.
• Biochemical Research: Potential use as a tool compound or probe for studying specific enzymatic or cellular pathways in academic and industrial labs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3,5a-Epoxy-2H,5aH,7H-[1,4]dioxepino[2,3-e]oxepino[2,3-d]pyrazino[1,2-a]pyrimidin-8(9H)-one, 3,4-dihydro-4,4-dimethyl-10-(1-methylethyl)-7-(phenylmethyl)-, (3R,5aS,7S,16aR)-
CAS No.	1623451-72-8
Molecular Formula	C25H28N2O5
Molecular Weight	436.50 g/mol
Synonyms	(3R,5aS,7S,16aR)-3,4-Dihydro-4,4-dimethyl-10-isopropyl-7-benzyl-3,5a-epoxy-2H,5aH,7H-[1,4]dioxepino[2,3-e]oxepino[2,3-d]pyrazino[1,2-a]pyrimidin-8(9H)-one; Complex Oxepino-Pyrazino-Pyrimidinone Derivative; CAS 1623451-72-8; 3,5a-Epoxy-2H,5aH,7H-[1,4]dioxepino[2,3-e]oxepino[2,3-d]pyrazino[1,2-a]pyrimidin-8(9H)-one, 3,4-dihydro-4,4-dimethyl-10-(1-methylethyl)-7-(phenylmethyl)-, (3R,5aS,7S,16aR)- Isomer; Benzyl-Substituted Dioxepinooxepinopyrazinopyrimidinone; Stereoisomer 1623451-72-8
EINECS	Contact for details

Quality Control

Our 3,5a-Epoxy-2H,5aH,7H-[1,4]dioxepino[2,3-e]oxepino[2,3-d]pyrazino[1,2-a]pyrimidin-8(9H)-one, 3,4-dihydro-4,4-dimethyl-10-(1-methylethyl)-7-(phenylmethyl)-, (3R,5aS,7S,16aR)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with rigorous pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) with batch-specific data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.