Description

tert-butyl (33R,34S,35S,91R,92R,5S)-5-(tert-butyl)-34-ethyl-14,14-difluoro-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxylate is a sophisticated, high-purity organic compound designed for advanced research and development. Its complex, multi-cyclic structure featuring quinoxaline, pyrrolidine, and cyclopropane motifs makes it a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). This compound is essential for pharmaceutical chemists and R&D teams in drug discovery programs, particularly those targeting complex disease pathways.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, especially in oncology and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of new chemical entities.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant scale.
• High-Value Fine Chemical Production: Manufactured for supply to contract research organizations (CROs) and pharmaceutical companies requiring specialized intermediates.
• Academic Research: Utilized in university and institutional labs for developing new synthetic methodologies involving complex heterocycles.

Basic Information

Product Name	tert-butyl (33R,34S,35S,91R,92R,5S)-5-(tert-butyl)-34-ethyl-14,14-difluoro-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxylate
CAS No.	1535212-05-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1535212-05-5; tert-Butyl complex cyclotetradecaphane carboxylate; Advanced quinoxaline-pyrrolidine hybrid intermediate; Multi-cyclic fluorinated pharmaceutical building block; (33R,34S,35S,91R,92R,5S)-5-(tert-butyl)-34-ethyl-14,14-difluoro-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development under cGMP guidelines where required, ensuring the material is suitable for demanding pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.