Description

L-Leucine, L-tryptophyl-L-α-glutamyl-L-α-glutamyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-α-glutamyl-L-isoleucyl-L-asparaginyl-L-asparaginyl-L-tyrosyl-L-threonyl-N6-[2-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]acetyl]-L-lysyl-L-leucyl-L-isoleucyl-L-histidyl-L-α-glutamyl-L-leucyl-L-isoleucyl-L-α-glutamyl-L-α-glutamyl-L-seryl-L-glutaminyl-L-asparaginyl-L-glutaminyl-L-glutaminyl-L-α-glutamyl-L-lysyl-L-asparaginyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-leucyl- is a complex, high-purity synthetic peptide with a specific and sophisticated molecular architecture. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the fields of targeted therapeutics and diagnostic agents. It is primarily utilized by biotechnology companies, academic research institutions, and pharmaceutical developers engaged in cutting-edge drug discovery programs.

Application

• Pharmaceutical Research: As a key intermediate or active pharmaceutical ingredient (API) in the development of novel peptide-based therapeutics.
• Targeted Drug Delivery: Utilized in the design of drug conjugates where the peptide sequence facilitates specific tissue or cellular targeting.
• Diagnostic Imaging: Potential use in the synthesis of contrast agents or radiotracers for medical imaging techniques like PET or SPECT.
• Bioconjugation: The maleimide functional group (from the 2,5-dioxopyrrolidinyl moiety) enables site-specific conjugation to thiol groups on proteins, antibodies, or other carriers.
• Biochemical Research: Serves as a specialized reagent in proteomics, signal transduction studies, and enzyme-substrate interaction assays.
• Preclinical Development: Used in in vitro and in vivo studies to evaluate pharmacokinetics, efficacy, and safety profiles of new drug candidates.

Basic Information

Item	Details
Product Name	L-Leucine, L-tryptophyl-L-α-glutamyl-L-α-glutamyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-α-glutamyl-L-isoleucyl-L-asparaginyl-L-asparaginyl-L-tyrosyl-L-threonyl-N6-[2-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]acetyl]-L-lysyl-L-leucyl-L-isoleucyl-L-histidyl-L-α-glutamyl-L-leucyl-L-isoleucyl-L-α-glutamyl-L-α-glutamyl-L-seryl-L-glutaminyl-L-asparaginyl-L-glutaminyl-L-glutaminyl-L-α-glutamyl-L-lysyl-L-asparaginyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-leucyl-
CAS No.	1417179-66-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Maleimide-PEG3-Gastrin I (human) fragment 2-17 amide; Gastrin I (2-17), N6-[(3-maleimidopropionyl)amino-3,6,9,12-tetraoxatetradecanoyl]-; Peptide-drug conjugate intermediate; Targeted peptide conjugate; Synthetic gastrin fragment derivative; Thiol-reactive peptide; Bioconjugation-ready peptide
EINECS	Contact for details

Quality Control

This high-value peptide is manufactured under strict GMP-like conditions to ensure batch-to-batch consistency and integrity. Quality is verified through a comprehensive suite of analytical techniques including HPLC for purity, MS for identity confirmation, and amino acid analysis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.