Description

2-[[(3aR,4S,6R,6aS)-6-(7-azanyl-5-propylsulfanyl-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethanol is a sophisticated nucleoside analog derivative, serving as a critical pharmaceutical intermediate or active pharmaceutical ingredient (API) building block. Its complex heterocyclic structure, featuring a fused triazolopyrimidine core, makes it a valuable scaffold for the development of novel therapeutic agents. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of antiviral and anticancer drugs.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex nucleoside-based Active Pharmaceutical Ingredients (APIs).
• Antiviral Drug Research: Used in the research and development of novel antiviral agents, particularly those targeting viral polymerases.
• Oncology Research: Serves as a precursor in the synthesis of potential anticancer compounds that interfere with DNA/RNA synthesis.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and biochemical assays.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for advanced pharmaceutical compounds.

Basic Information

Item	Detail
Product Name	2-[[(3aR,4S,6R,6aS)-6-(7-azanyl-5-propylsulfanyl-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethanol
CAS No.	1354945-69-9
Molecular Formula	C17H25N5O4S
Molecular Weight	395.48 g/mol
Synonyms	2-(((3aR,4S,6R,6aS)-6-(7-Amino-5-(propylthio)-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol; 7-Amino-3-((3aR,4S,6R,6aS)-4-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-6-yl)-5-(propylthio)-[1,2,3]triazolo[4,5-d]pyrimidine; Nucleoside triazolopyrimidine derivative; Propylthio-triazolopyrimidine ethanol nucleoside; Advanced pharmaceutical intermediate 1354945-69-9; Triazolopyrimidine nucleoside analog
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for research and development under a quality management system. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. For GMP-grade material intended for pharmaceutical use, please contact us to discuss specific regulatory requirements and custom synthesis capabilities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.