Description

(2S,3R)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(((2S,3R,4R,5R,6R)-3-acetaMido-6-((((2R,3R,4R,5S,6R)-3-acetaMido-4,5-diacetoxy-6-(acetoxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)Methyl)-5-acetoxy-4-(((2R,3R,4S,5S,6R)-3,4,5-triacetoxy-6-(acetoxyMethyl)t is a complex, high-purity synthetic intermediate, specifically a protected glycopeptide building block. It is a critical component for the controlled synthesis of advanced glycoconjugates and oligosaccharides. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel glycoprotein-based therapeutics and diagnostic agents.

Application

• Pharmaceutical Research & Development: As a key building block in the solid-phase and solution-phase synthesis of complex glycopeptides and glycoproteins for drug discovery.
• Antibody-Drug Conjugate (ADC) Development: For the site-specific conjugation of payloads via glycan engineering to create next-generation targeted cancer therapies.
• Glycobiology Studies: Used as a standardized intermediate to investigate glycosylation patterns, enzyme functions, and carbohydrate-protein interactions.
• Synthesis of Vaccine Components: Enables the production of well-defined carbohydrate antigens for conjugate vaccine development against bacterial pathogens.
• Diagnostic Reagent Manufacturing: Serves as a precursor for labeled glycans used in diagnostic assays, lectin arrays, and biosensors.
• Process Development for Biologics: Supports the development of manufacturing processes for glycosylated biopharmaceuticals, ensuring consistency and quality.

Basic Information

Product Name	(2S,3R)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(((2S,3R,4R,5R,6R)-3-acetaMido-6-((((2R,3R,4R,5S,6R)-3-acetaMido-4,5-diacetoxy-6-(acetoxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)Methyl)-5-acetoxy-4-(((2R,3R,4S,5S,6R)-3,4,5-triacetoxy-6-(acetoxyMethyl)t
CAS No.	1240252-34-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-Thr(Ac4GlcNAcβ1-6(Ac4GlcNAcβ1-3)AcGalNAcα)-OH building block; Glycopeptide building block, Fmoc-protected; Fmoc-Thr(Ac8-di-GlcNAc-GalNAcα)-OH; CAS 1240252-34-9; Protected Tn antigen glycopeptide precursor; Fmoc-Thr[Ac4GlcNAcβ(1-6)[Ac4GlcNAcβ(1-3)]AcGalNAcα]-OH; Complex glycosylated amino acid derivative; Fmoc-O-glycosylated threonine derivative
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality control protocols suitable for research and pharmaceutical development. Each batch is characterized using advanced analytical techniques including HPLC, LC-MS, and NMR to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support regulatory filings and ensure batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.