Description

Histidine CAS NO 71-00-1 is an essential α-amino acid, serving as a fundamental building block for proteins and a critical precursor in numerous biochemical pathways. Its unique chemical structure, featuring an imidazole side chain, makes it indispensable for applications requiring precise pH buffering and metal ion chelation. This versatile compound is in high demand across the pharmaceutical, nutraceutical, and food industries, where its purity and consistency are paramount for product efficacy and safety.

Application

• Pharmaceutical Intermediates: A key raw material in the synthesis of active pharmaceutical ingredients (APIs), particularly for cardioprotective and anti-inflammatory drugs.
• Infusion & Parenteral Nutrition: A vital component of amino acid solutions for clinical nutrition, supporting patient recovery and metabolic function.
• Dietary Supplements & Sports Nutrition: Used in formulations aimed at muscle recovery, endurance, and overall metabolic health due to its role in carnosine synthesis.
• Food & Flavor Enhancement: Employed as a nutritional fortifier and flavor precursor in specialized food products and seasonings.
• Biochemical Research & Cell Culture: An essential component of cell culture media, buffers, and reagents used in life science research and biomanufacturing.
• Cosmetic & Personal Care: Incorporated into skincare formulations for its antioxidant properties and role in maintaining skin health.

Basic Information

Product Name	Histidine
CAS No.	71-00-1
Molecular Formula	C6H9N3O2
Molecular Weight	155.15 g/mol
Synonyms	L-Histidine; (S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid; Histidine (USP); Histidine (EP); Glyoxaline-5-alanine; 2-Amino-3-(4-imidazolyl)propionic acid; His; H
EINECS	200-745-3

Quality Control

Our Histidine is manufactured under strict quality management systems. We offer grades compliant with major pharmacopoeial standards, including USP, EP, JP, and FCC, ensuring suitability for high-value applications. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) documenting full specifications are provided to guarantee traceability and compliance with your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the original container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.5% - 101.0%
Specific Rotation	+38.5° to +41.5°
Loss on Drying	≤ 0.2%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 0.5%
Chloride (Cl)	≤ 0.02%
Sulfate (SO4)	≤ 0.02%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.