Description

n-Acetyl-L-Leucine is a high-purity derivative of the essential amino acid L-Leucine, widely recognized for its role in biochemical research and pharmaceutical synthesis. This compound is valued for its consistent quality and stability, making it a reliable building block for advanced applications. It is primarily utilized by research institutions, pharmaceutical manufacturers, and nutraceutical companies engaged in peptide synthesis, metabolic studies, and the development of specialized formulations.

Application

• Pharmaceutical Intermediates: A key chiral building block in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Nutraceutical Formulations: Incorporated into advanced dietary supplements and clinical nutrition products requiring specific amino acid derivatives.
• Cosmetic Actives: Employed in the development of high-end skincare products for its potential role in protein synthesis and skin conditioning.
• Chemical Synthesis: Serves as a protected leucine derivative in organic and medicinal chemistry for constructing complex molecular architectures.

Basic Information

Product Name	n-Acetyl-L-Leucine
CAS No.	1188-21-2
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	N-Acetyl-L-leucine; (2S)-2-Acetamido-4-methylpentanoic acid; L-Leucine, N-acetyl-; Ac-Leu-OH; N-Acetylleucine; NSC 3346; Acetyl-L-leucine; (S)-2-Acetamido-4-methylpentanoic acid
EINECS	214-702-3

Quality Control

Our n-Acetyl-L-Leucine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and specific impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.