Description

2-Ketoglutaric Acid is a key dicarboxylic acid and a crucial intermediate in the Krebs cycle, essential for cellular energy metabolism. Its high purity and consistent quality make it a critical raw material for demanding research and industrial biosynthesis processes. This compound is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and biotechnology sectors, as well as by research institutions.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of various active pharmaceutical ingredients (APIs), including certain nootropic and metabolic agents.
• Cell Culture & Fermentation: Serves as a key component in cell culture media and fermentation broths to support cell growth and the production of recombinant proteins and other biologics.
• Dietary Supplement & Nutraceutical Formulation: Used in the production of supplements targeting mitochondrial health and energy metabolism.
• Biochemical Research: An essential substrate and standard in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Cosmetic Ingredients: Incorporated into advanced skincare formulations for its role in cellular energy and potential anti-aging properties.
• Industrial Biotechnology: Acts as a building block in microbial fermentation processes for the bio-based production of chemicals like glutaric acid.

Basic Information

Product Name	2-Ketoglutaric Acid
CAS No.	328-50-7
Molecular Formula	C5H6O5
Molecular Weight	146.10 g/mol
Synonyms	α-Ketoglutaric Acid; 2-Oxoglutaric Acid; 2-Oxopentanedioic Acid; Oxoglutaric Acid; AKG; 2-Ketoglutarate; 2-Oxoglutarate; Ketoglutaric Acid
EINECS	206-330-3

Quality Control

Our 2-Ketoglutaric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.