Description

Sodium Taurocholate is a high-purity conjugated bile salt, a critical biochemical reagent and pharmaceutical intermediate. Its primary value lies in its exceptional ability to solubilize lipids and cholesterol, making it indispensable for research and manufacturing processes that require precise membrane disruption or emulsification. This product is essential for pharmaceutical development, diagnostic reagent formulation, and advanced life science research, serving industries focused on digestive health, drug delivery systems, and in-vitro diagnostics.

Application

• Pharmaceutical Excipient & API Intermediate: Used in the formulation of hepatobiliary drugs and as a critical component in drug delivery systems to enhance the solubility and absorption of poorly water-soluble active pharmaceutical ingredients (APIs).
• In-Vitro Diagnostic (IVD) Reagents: A key component in clinical chemistry reagents for enzymatic assays, particularly those measuring liver function and bile acid metabolism.
• Cell Biology & Biochemistry Research: Employed as a detergent for membrane protein solubilization, in cell lysis buffers, and to create micelles for studying lipid-protein interactions.
• Microbiology & Cell Culture: Used in selective media and as a supplement in mammalian cell culture to aid in lipid digestion and transport.
• Reference Standard & Calibrator: Serves as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quantifying bile acids in biological samples.

Basic Information

Product Name	Sodium Taurocholate
CAS No.	145-42-6
Molecular Formula	C26H44NNaO7S
Molecular Weight	537.70 g/mol
Synonyms	Taurocholic Acid Sodium Salt; Cholyltaurine Sodium Salt; Sodium Cholyltaurinate; N-Choloyltaurine Sodium Salt; 3α,7α,12α-Trihydroxy-5β-cholan-24-oyltaurine Sodium Salt; Taurocholate; Taurocholic Acid Salt; TCA-Na
EINECS	205-653-2

Quality Control

Our Sodium Taurocholate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We can supply material compliant with relevant pharmacopeial standards (e.g., USP-NF) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Microbial Limits	Meets specified criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.