Description

L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-α-aspartyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1→6),(2→10),(5→13)-tris(disulfide) is a complex, cyclic peptide featuring a defined three-disulfide bridge structure, which is critical for its biological stability and activity. This compound matters as a high-purity, structurally defined reference standard and key intermediate for advanced pharmaceutical research and development. It is primarily needed by biotechnology and pharmaceutical companies engaged in peptide-based drug discovery, particularly for targeting specific protein-protein interactions and developing novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and method validation in the analysis of complex peptide therapeutics.
• Drug Discovery Intermediate: Serves as a critical building block or precursor in the synthesis of novel peptide-based drugs targeting metabolic and neurological pathways.
• Biochemical Research: Employed in academic and industrial research to study disulfide bond formation, peptide folding, and structure-activity relationships (SAR).
• Peptide Library Synthesis: Utilized in the generation of specialized peptide libraries for high-throughput screening (HTS) to identify new bioactive compounds.
• Diagnostic Reagent Development: Acts as a key component in the development of sensitive and specific immunoassays or biosensors.
• Cosmeceutical Active Ingredient: Potential application in high-end skincare formulations targeting specific cellular processes due to its peptide nature.

Basic Information

Product Name	L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-α-aspartyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1→6),(2→10),(5→13)-tris(disulfide)
CAS No.	1207977-38-5
Molecular Formula	C68H98N20O26S6
Molecular Weight	1748.0 g/mol (approx.)
Synonyms	Cyclic (Cys-Cys-Glu-Tyr-Cys-Cys-Asp-Pro-Ala-Cys-Thr-Gly-Cys) tris(disulfide); [Tyr1, Cys2, Cys3, Glu4, Tyr5, Cys6, Cys7, Asp8, Pro9, Ala10, Cys11, Thr12, Gly13, Cys14]-cyclic (1-6,2-10,5-13)-tris(disulfide) peptide; H-Tyr-Cys-Cys-Glu-Tyr-Cys-Cys-Asp-Pro-Ala-Cys-Thr-Gly-Cys-OH (cyclic tris-disulfide); Cyclic peptide with three disulfide bridges (1-6, 2-10, 5-13); CAS 1207977-38-5; Complex cyclic cystine peptide; Multi-disulfide bridged tyrosine peptide.
EINECS	Contact for details

Quality Control

Our L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-α-aspartyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1→6),(2→10),(5→13)-tris(disulfide) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure structural integrity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container must be sealed under an inert atmosphere or with desiccant after opening. For long-term storage, maintain under argon or nitrogen atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.