Description

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[2,2,2-trifluoro-1-[(3-Methyl-1-oxobutyl)aMino]-1-(trifluoroMethyl)ethyl]-1-piperazinyl]- is a high-purity, advanced pharmaceutical intermediate with a complex molecular structure designed for targeted activity. This compound is critical for research and development in the synthesis of novel therapeutic agents, particularly within the fluoroquinolone antibiotic class. It serves as a key building block for pharmaceutical manufacturers and R&D institutions focused on developing next-generation antibacterial treatments.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A crucial synthetic precursor in the manufacturing of advanced fluoroquinolone antibiotics.
• Pharmaceutical R&D: Used in medicinal chemistry for the discovery and structural optimization of new antibacterial compounds.
• Process Chemistry: Serves as a key intermediate in scale-up and process development for commercial drug production.
• Reference Standard: Employed as an analytical standard for quality control and regulatory compliance in API manufacturing.
• Biochemical Research: Utilized in studies investigating bacterial DNA gyrase and topoisomerase IV inhibition mechanisms.

Basic Information

Product Name	3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[2,2,2-trifluoro-1-[(3-Methyl-1-oxobutyl)aMino]-1-(trifluoroMethyl)ethyl]-1-piperazinyl]-
CAS No.	196401-21-5
Molecular Formula	C24H26F7N4O4
Molecular Weight	552.48 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-{2,2,2-trifluoro-1-[(3-methyl-1-oxobutyl)amino]-1-(trifluoromethyl)ethyl}-1-piperazinyl)-3-quinolinecarboxylic acid; WCK 771 Intermediate; Levonadifloxacin Alalevonadifloxacin Intermediate; (S)-(-)-9-Fluro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid L-arginine salt derivative; Benzo[i,j]quinolizine-2-carboxylic acid derivative; Advanced Fluoroquinolone Intermediate; Antibacterial Research Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict cGMP (current Good Manufacturing Practice) guidelines to ensure batch-to-batch consistency and traceability. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles against established specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a dry environment and opened under controlled conditions to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.