Description

Gemifloxacin Mesylate is the mesylate salt form of a potent, broad-spectrum fluoroquinolone antibiotic. This compound is critical for pharmaceutical research and development, offering enhanced solubility and stability for formulation studies. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of advanced antibacterial therapies targeting respiratory and other systemic infections.

Application

• Pharmaceutical Active Ingredient (API): Serves as the key active component in the formulation of finished antibacterial drug products.
• Reference Standard: Used as a certified reference material in analytical laboratories for quality control, method validation, and regulatory compliance testing.
• Research & Development: Essential for preclinical and clinical studies investigating the efficacy, pharmacokinetics, and safety profile of gemifloxacin-based treatments.
• Antibacterial Susceptibility Testing: Employed in microbiological assays to determine bacterial resistance patterns and minimum inhibitory concentrations (MIC).
• Formulation Development: Used in studies to develop various dosage forms such as tablets, capsules, and injectables, leveraging its mesylate salt properties for improved bioavailability.

Basic Information

Product Name	Gemifloxacin Mesylate
CAS No.	210353-53-0
Molecular Formula	C20H24FN5O4 • CH4O3S
Molecular Weight	485.51 g/mol
Synonyms	Gemifloxacin methanesulfonate; SB-265805S; LB-20304a; 7-[(4Z)-3-(Aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate salt; (Z)-7-(3-Aminomethyl-4-methoxyimino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate; Factive Mesylate
EINECS	Contact for details

Quality Control

Our Gemifloxacin Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and stringent control of residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with relevant pharmacopeial guidelines and customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Microbial Enumeration	Complies with Ph. Eur. 2.6.12 / USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.