Description

D-Ofloxacin is the dextrorotatory enantiomer of the broad-spectrum fluoroquinolone antibiotic ofloxacin, identified by CAS NO 100986-86-5. This optically active compound is valued for its targeted antibacterial activity and serves as a critical chiral intermediate in advanced pharmaceutical synthesis. It is essential for research institutions and manufacturers developing enantiomerically pure antimicrobial agents and novel therapeutic formulations.

Application

• As a key chiral intermediate in the synthesis of enantiomerically pure fluoroquinolone antibiotics.
• For pharmaceutical research and development of novel antibacterial agents with improved efficacy and reduced side-effect profiles.
• In the preparation of reference standards and analytical markers for quality control in drug manufacturing.
• For biochemical studies investigating the mechanism of action and structure-activity relationships of quinolone antibiotics.
• Use in the development of combination therapies and specialized dosage forms.

Basic Information

Product Name	D-Ofloxacin
CAS No.	100986-86-5
Molecular Formula	C18H20FN3O4
Molecular Weight	361.37 g/mol
Synonyms	(R)-Ofloxacin; Dextro-Ofloxacin; (3R)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid; (R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid; D-OFX; Right-handed ofloxacin
EINECS	Contact for details

Quality Control

Our D-Ofloxacin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets high-grade pharmaceutical standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Chiral Purity (Enantiomeric Excess)	≥99.0%
Related Substances (HPLC)	Total impurities ≤1.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.