Description

Nalidixic Acid Sodium Salt Hydrate 97 is the sodium salt derivative of the first-generation quinolone antibiotic, nalidixic acid. This compound serves as a critical pharmaceutical intermediate and a reference standard in analytical and research settings. It is primarily utilized by manufacturers and researchers in the pharmaceutical, biotechnology, and academic research sectors for developing and studying antimicrobial agents.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of more complex quinolone and fluoroquinolone antibiotic derivatives.
• Analytical Reference Standard: Used in high-performance liquid chromatography (HPLC), mass spectrometry, and other analytical methods for quality control, method development, and validation.
• Microbiological Research: Employed in laboratory studies to investigate bacterial DNA gyrase inhibition, mechanisms of antibiotic action, and bacterial resistance patterns.
• Biochemical Assay Development: Utilized as a reagent or control in enzymatic assays and other in-vitro test systems targeting topoisomerase enzymes.
• Academic & Industrial R&D: Serves as a foundational compound for discovering and developing new antibacterial agents with improved efficacy and safety profiles.

Basic Information

Product Name	Nalidixic Acid Sodium Salt Hydrate 97
CAS No.	15769-77-4
Molecular Formula	C12H11N2NaO3 · xH2O
Molecular Weight	254.22 g/mol (anhydrous basis)
Synonyms	Nalidixic Acid Sodium Salt; Sodium Nalidixate; 1-Ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic Acid Sodium Salt; 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate Sodium Salt; Win 18,320 Sodium Salt; Nalidixic Acid Na Salt; Negram Sodium Salt; Nalidixin Sodium.
EINECS	Contact for details

Quality Control

Our Nalidixic Acid Sodium Salt Hydrate is produced and tested under a rigorous quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specific results for assay, impurities, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	97.0% min. (on anhydrous basis)
Water Content (KF)	Contact for details
pH (5% solution)	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	Contact for details
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.