Description

Levofloxacin CAS NO 100986-85-4 is a synthetic broad-spectrum fluoroquinolone antibiotic, representing the pharmacologically active L-isomer of ofloxacin. Its primary value lies in its potent antibacterial activity against a wide range of Gram-positive and Gram-negative pathogens, including multi-drug resistant strains. This high-purity active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers developing and producing critical antibiotic formulations for the treatment of severe respiratory, skin, and urinary tract infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of finished dosage forms, including tablets, capsules, and injectable solutions.
• Antibacterial Formulations: Formulation of medications for treating community-acquired pneumonia, chronic bronchitis, and skin structure infections.
• Ophthalmic Solutions: Production of sterile eye drops for the treatment of bacterial conjunctivitis.
• Veterinary Medicine: Development of antibacterial treatments for veterinary applications, under appropriate regulatory guidelines.
• Research & Development: Serves as a reference standard and key intermediate in pharmaceutical R&D for novel antibacterial agents.
• Hospital & Clinical Use: Bulk supply for hospital pharmacies preparing specific intravenous or oral solutions.

Basic Information

Product Name	Levofloxacin
CAS No.	100986-85-4
Molecular Formula	C18H20FN3O4
Molecular Weight	361.37 g/mol
Synonyms	(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid; Levofloxacin hemihydrate; (S)-(-)-Ofloxacin; Levaquin; Tavanic; Cravit; Iquix; Quixin; LVFX
EINECS	Contact for details

Quality Control

Our Levofloxacin is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards including USP, EP, and JP. Every batch undergoes comprehensive analytical testing, including assay, identification, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results against specifications is provided with each shipment to ensure full traceability and quality assurance for our B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to slightly yellow crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water Content (KF)	≤ 1.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%
Optical Rotation	-92° to -99°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.