Description

Tosufloxacin Tosilate is the tosylate salt form of tosufloxacin, a potent third-generation fluoroquinolone antibiotic. This compound is a key pharmaceutical intermediate valued for its enhanced stability and solubility profile compared to the free base. It is primarily utilized in the research and development of advanced antibacterial agents targeting a broad spectrum of Gram-positive and Gram-negative pathogens. Industries involved in active pharmaceutical ingredient (API) synthesis and advanced antimicrobial research are the primary users of this high-purity material.

Application

• Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of Tosufloxacin-based antibiotic formulations.
• Antimicrobial Research: Used in preclinical and clinical research to study the efficacy, pharmacokinetics, and mechanisms of advanced fluoroquinolone antibiotics.
• Reference Standard: Serves as a high-purity chemical reference standard for quality control and analytical method development in pharmaceutical laboratories.
• API Manufacturing: Employed in the scaled-up production of Tosufloxacin Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Veterinary Medicine Development: Investigated for potential applications in developing antibacterial treatments for veterinary use.

Basic Information

Product Name	Tosufloxacin Tosilate
CAS No.	100490-36-6
Molecular Formula	C₂₆H₂₅F₃N₄O₇S
Molecular Weight	570.56 g/mol
Synonyms	Tosufloxacin p-Toluenesulfonate; Tosufloxacin Tosylate; (+/-)-7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid 4-methylbenzenesulfonate; T-3262 Tosylate; Ozex Tosilate; 1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo, 4-methylbenzenesulfonate
EINECS	Contact for details

Quality Control

Our Tosufloxacin Tosilate is manufactured and tested to meet stringent quality standards suitable for pharmaceutical research and development. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and specific tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Single Maximum Impurity	≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.