Description

L-Threonine, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide is a sophisticated, high-purity synthetic peptide derivative designed for advanced research and development. This compound is critical for applications requiring precise molecular targeting and conjugation, particularly in the development of novel diagnostic and therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, biotechnology firms, and academic research institutions focused on oncology, diagnostic imaging, and targeted drug delivery systems.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or targeting moiety in the synthesis of novel peptide-based therapeutics and radiopharmaceuticals.
• Diagnostic Imaging Agents: Used in the development of contrast agents for advanced imaging techniques such as MRI, due to its chelating properties from the tetraazacyclododecane (DOTA) core.
• Targeted Drug Delivery Systems: Incorporated into drug conjugates designed to deliver cytotoxic agents or radionuclides specifically to tumor cells.
• Bioconjugation & Probe Development: Acts as a versatile scaffold for attaching fluorescent dyes, affinity tags, or other functional groups for cellular and molecular biology studies.
• Preclinical Studies: Employed in animal models to evaluate the pharmacokinetics, biodistribution, and efficacy of new therapeutic candidates.

Basic Information

Item	Details
Product Name	L-Threonine, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide
CAS No.	177943-88-3
Molecular Formula	C73H100N16O23S2
Molecular Weight	1681.8 g/mol (Contact for details)
Synonyms	DOTA-TATE; DOTA-(Tyr3)-octreotate; [DOTA0,Tyr3]Octreotate; DOTA-Tyr3-Octreotate; Ga-68 DOTA-TATE precursor; DOTATATE; DOTA-Octreotate; (Tyr3)-octreotate-DOTA
EINECS	Contact for details

Quality Control

Our L-Threonine, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide is manufactured under strict quality systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.