Description

L-Aspartic acid, N-[1-[[(1,1-dimethylethyl)amino]carbonyl]-2-methylpropyl]-, 4-[1-[[(1,1-dimethylethyl)amino]carbonyl]-2-methylpropyl] 1-methyl ester, [S-(R*,S*)]- (9CI) CAS NO 169533-23-7 is a specialized, high-purity synthetic amino acid derivative. This compound is valued for its role as a key chiral building block and intermediate in advanced organic synthesis. It is primarily required by research institutions and pharmaceutical development companies engaged in the creation of novel peptides, protease inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new drug candidates, particularly in the field of protease inhibitors.
• Peptide Synthesis: Used as a protected aspartic acid derivative for the solid-phase or solution-phase synthesis of complex peptides and proteins.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway research due to its specific stereochemistry.
• Organic Synthesis Building Block: Employed in asymmetric synthesis to introduce specific chiral centers into more complex organic molecules.
• Reference Standard: Utilized in analytical laboratories as a high-purity reference material for method development and quality control.

Basic Information

Item	Details
Product Name	L-Aspartic acid, N-[1-[[(1,1-dimethylethyl)amino]carbonyl]-2-methylpropyl]-, 4-[1-[[(1,1-dimethylethyl)amino]carbonyl]-2-methylpropyl] 1-methyl ester, [S-(R*,S*)]- (9CI)
CAS No.	169533-23-7
Molecular Formula	C19H35N3O5
Molecular Weight	385.50 g/mol
Synonyms	Boc-L-tert-Leu-Asp(OBzl)-OtBu; (2S)-2-[(2S)-2-[(tert-Butoxycarbonyl)amino]-3,3-dimethylbutanamido]butanedioic acid 1-tert-butyl 4-benzyl ester; N-Boc-L-tert-leucyl-L-aspartic acid β-benzyl α-tert-butyl ester; Boc-L-tert-leucyl-L-aspartic acid 1-tert-butyl 4-benzyl ester; Aspartic acid derivative (Boc-L-tert-Leu-Asp(OBzl)-OtBu); Protected L-Aspartic acid derivative; CAS 169533-23-7
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized using techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.