Description

Glycine, O-ethyl-N-(3-mercapto-1-oxopropyl)-D-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-, cyclic (1→5)-disulfide is a complex, synthetic cyclic peptide derivative with a specific disulfide bridge. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the design of novel peptide-based therapeutics and biochemical probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, drug discovery, and the study of receptor-ligand interactions.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis of novel peptide drugs targeting specific biological pathways.
• Biochemical Probes: Used in scientific studies to investigate enzyme inhibition, receptor binding, and cellular signaling mechanisms due to its specific structural motifs.
• Peptide Library Synthesis: A valuable building block for creating diverse peptide libraries for high-throughput screening in drug discovery campaigns.
• Academic Research: Employed in university and institutional labs for advanced studies in organic synthesis, peptide folding, and structure-activity relationships (SAR).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Glycine, O-ethyl-N-(3-mercapto-1-oxopropyl)-D-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-, cyclic (1→5)-disulfide
CAS No.	168102-69-0
Molecular Formula	C₄₇H₇₄N₁₂O₁₅S₂
Molecular Weight	1119.3 g/mol
Synonyms	Cyclo(-D-Tyr(Et)-Ile-Thr-Asn-Cys-Pro-Orn-); [D-Tyr(OEt)¹,Ile²,Thr³,Asn⁴,Cys⁵,Pro⁶,Orn⁷]-Cyclosporin A Fragment (5-11) Disulfide; H-D-Tyr(OEt)-Ile-Thr-Asn-Cys-Pro-Orn-OH (cyclic 1-5 disulfide); Cyclic Peptide Disulfide Derivative; CAS 168102-69-0; O-Ethyl-N-(3-mercapto-1-oxopropyl)-D-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-glycine cyclic (1→5)-disulfide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for research and development purposes, with specifications typically focused on high purity (≥95% by HPLC) and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results for assay, purity, and related substances are available upon request. Quality is managed under a GMP-compliant quality system for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For extended storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.