Description

H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH is a synthetic peptide of significant interest in advanced pharmaceutical research and development. This compound serves as a critical research-grade intermediate for investigating complex biological pathways and developing novel therapeutic agents. It is primarily sought by biopharmaceutical companies, contract research organizations (CROs), and academic research institutions engaged in peptide-based drug discovery and biochemical studies.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the discovery and optimization of novel peptide therapeutics.
• Biochemical Assay Development: Utilized as a substrate, inhibitor, or ligand in enzymatic and receptor-binding studies to elucidate biological mechanisms.
• Proteomics and Signal Transduction Research: Employed in studies investigating protein-protein interactions, cellular signaling cascades, and post-translational modifications.
• Antibody Production: Can be used as an immunogen for generating specific antibodies for diagnostic or research applications.
• High-Throughput Screening (HTS): Integrated into screening libraries to identify potential drug candidates targeting specific peptide-binding sites.
• Structure-Activity Relationship (SAR) Studies: Serves as a core structure for analog synthesis to understand the impact of specific amino acid residues on biological activity.

Basic Information

Item	Details
Product Name	H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH
CAS No.	136461-80-8
Molecular Formula	C205H310N56O66S2
Molecular Weight	4538.1 g/mol (theoretical)
Synonyms	Peptide TFA (44 AA); [Tyr1,Leu2,Tyr3,Gln4,Trp5,Leu6,Gly7,Ala8,Pro9,Val10,Pro11,Tyr12,Pro13,Asp14,Pro15,Leu16,Gla17,Pro18,Arg19,Arg20,Gla21,Val22,Cys23,Gla24,Leu25,Asn26,Pro27,Asp28,Cys29,Asp30,Glu31,Leu32,Ala33,Asp34,His35,Ile36,Gly37,Phe38,Gln39,Glu40,Ala41,Tyr42,Arg43,Arg44,Phe45,Tyr46,Gly47,Pro48,Val49]-peptide; Synthetic 49-mer peptide; Research Peptide 136461-80-8; H-Tyr-Leu-Tyr-Gln-Trp-Leu-Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-Gla-Pro-Arg-Arg-Gla-Val-Cys-Gla-Leu-Asn-Pro-Asp-Cys-Asp-Glu-Leu-Ala-Asp-His-Ile-Gly-Phe-Gln-Glu-Ala-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val-OH
EINECS	Contact for details

Quality Control

This high-purity peptide is manufactured under controlled GMP-like conditions to ensure batch-to-batch consistency and reliability for critical research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and amino acid analysis. A detailed Certificate of Analysis (COA) is provided with each batch, documenting purity, identity, and other critical parameters to support regulatory submissions and research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere or with desiccant. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Amino Acid Analysis	Within ±10% of theoretical composition
Water Content (KF)	≤ 5.0%
Acetate/TFA Content (HPLC)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.