Description

N-[N-Hexadecanoyl-L-Pro-N-methyl-D-Leu-]cyclo[L-Thr*-[(3S,4R)-3-hydroxy-4-isopropyl-γAbu-]-[(2S,4S)-4-hydroxy*-2,5-dimethyl-3-oxohexanoyl]-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-] is a complex, synthetic cyclic depsipeptide compound, representing a sophisticated class of molecules designed for advanced research and development. Its intricate structure, featuring multiple chiral centers and a unique macrocyclic scaffold, makes it a valuable tool for studying peptide conformation, receptor interactions, and as a potential precursor for novel bioactive agents. This high-purity compound is essential for pharmaceutical R&D, particularly in the fields of oncology, metabolic disorders, and antimicrobial research, where precise molecular architecture is critical for activity.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the discovery and development of novel peptide-based therapeutics.
• Oncology Research: Investigated for its potential as a targeted therapeutic agent or a delivery vehicle for anti-cancer drugs due to its complex, cell-penetrating structure.
• Metabolic Disorder Studies: Used in research targeting G-protein-coupled receptors (GPCRs) and other signaling pathways involved in metabolic regulation.
• Antimicrobial Agent Development: Explored for its potential to disrupt bacterial cell membranes or inhibit essential enzymes, given its depsipeptide nature.
• Chemical Biology & Proteomics: Employed as a molecular probe to study protein-protein interactions, enzyme inhibition, and cellular uptake mechanisms.
• Advanced Material Science: Potential use in the development of self-assembling peptides or biocompatible nanomaterials.

Basic Information

Item	Details
Product Name	N-[N-Hexadecanoyl-L-Pro-N-methyl-D-Leu-]cyclo[L-Thr*-[(3S,4R)-3-hydroxy-4-isopropyl-γAbu-]-[(2S,4S)-4-hydroxy*-2,5-dimethyl-3-oxohexanoyl]-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-]
CAS No.	130406-06-3
Molecular Formula	C66H108N8O14
Molecular Weight	1213.6 g/mol
Synonyms	Cyclic Depsipeptide 130406-06-3; N-Palmitoyl Cyclic Depsipeptide Derivative; Hexadecanoyl Cyclo(Thr*-γAbu*-Oxohexanoyl-Leu-Pro-DimethylTyr) Peptide; L-Thr*-[(3S,4R)-3-hydroxy-4-isopropyl-γAbu-]-[(2S,4S)-4-hydroxy*-2,5-dimethyl-3-oxohexanoyl] Cyclic Peptide; N-Methyl-D-Leu Cyclic Depsipeptide; Complex Macrocyclic Peptide Ester; Cyclo(L-Thr*-γAbu*-Oxohexanoyl-L-Leu-L-Pro-N,O-dimethyl-L-Tyr) N-Hexadecanoyl Derivative
EINECS	Contact for details

Quality Control

Our N-[N-Hexadecanoyl-L-Pro-N-methyl-D-Leu-]cyclo[L-Thr*-[(3S,4R)-3-hydroxy-4-isopropyl-γAbu-]-[(2S,4S)-4-hydroxy*-2,5-dimethyl-3-oxohexanoyl]-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure structural integrity. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research-grade material standards. Our commitment is to deliver high-purity, well-characterized compounds to support critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake. For extended storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.