Description

N-[N-[3-(4-Hydroxyphenyl)propanoyl]-L-Pro-N-methyl-D-Leu-]cyclo[L-Thr*-[(3S,4R)-3-hydroxy-4-isopropyl-γAbu-]-[(2S,4S)-4-hydroxy*-2,5-dimethyl-3-oxohexanoyl]-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-] is a complex, high-purity cyclic peptide derivative designed for advanced research and development. This compound is valued for its specific stereochemistry and functional groups, which are critical for modulating biological activity in pharmaceutical discovery. It serves as a key intermediate or reference standard for scientists in medicinal chemistry and pharmacology, particularly those developing novel peptide-based therapeutics.

Application

• Pharmaceutical Research & Development: Acts as a crucial intermediate in the synthesis of novel peptide drugs targeting specific receptors.
• Medicinal Chemistry: Used as a building block or a reference compound for structure-activity relationship (SAR) studies to optimize drug candidates.
• Biochemical Research: Serves as a tool compound for investigating peptide-protein interactions and enzymatic processes in vitro.
• Reference Standard: Provides a high-purity benchmark for analytical method development, validation, and quality control in API manufacturing.
• Pre-clinical Studies: Utilized in early-stage pharmacological evaluation and proof-of-concept testing for new therapeutic avenues.

Basic Information

Item	Detail
Product Name	N-[N-[3-(4-Hydroxyphenyl)propanoyl]-L-Pro-N-methyl-D-Leu-]cyclo[L-Thr*-[(3S,4R)-3-hydroxy-4-isopropyl-γAbu-]-[(2S,4S)-4-hydroxy*-2,5-dimethyl-3-oxohexanoyl]-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-]
CAS No.	130406-05-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cyclic Peptide Derivative 130406-05-2; Cyclo(L-Thr-L-γAbu(3-OH,4-iPr)-L-Leu-L-Pro-L-Tyr(Me2)) Derivative; N-Methyl-D-leucyl-N-[3-(4-hydroxyphenyl)propanoyl]-L-prolyl Cyclic Peptide; L-Threonine, cyclo derivative with other amino acids; Complex Cyclic Hexapeptide Analog; Peptidic Research Compound 130406-05-2; Cyclic Depsipeptide Intermediate
EINECS	Contact for details

Quality Control

Our N-[N-[3-(4-Hydroxyphenyl)propanoyl]-L-Pro-N-methyl-D-Leu-]cyclo[L-Thr*-[(3S,4R)-3-hydroxy-4-isopropyl-γAbu-]-[(2S,4S)-4-hydroxy*-2,5-dimethyl-3-oxohexanoyl]-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-] is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.