Description

2,2-Dimethyl-butanoic Acid [1S-[1a,3a,4aa,7,8(2S*,4S*),8a]]-8-[2-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3,7-dimethyl-1-naphthalenyl Ester is a complex, high-purity synthetic intermediate characterized by its specific stereochemistry and protective groups. This compound is of significant value in advanced organic synthesis, particularly for the construction of intricate molecular architectures. It is primarily required by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs) and other fine chemicals where precise stereochemical control is critical.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of complex drug candidates, especially in steroid or terpenoid-related pathways.
• Advanced Organic Synthesis: Used in research-scale reactions for constructing complex natural product analogs and exploring new synthetic methodologies.
• Process Chemistry Development: Employed in the optimization and scale-up of synthetic routes for target molecules in pilot plant settings.
• Academic & Industrial Research: A valuable reagent for chemists in universities and corporate R&D labs investigating structure-activity relationships (SAR) and new chemical entities.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in related synthetic processes.

Basic Information

Product Name	2,2-Dimethyl-butanoic Acid [1S-[1a,3a,4aa,7,8(2S*,4S*),8a]]-8-[2-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3,7-dimethyl-1-naphthalenyl Ester
CAS No.	125142-16-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(3S,4aR,6aR,7R,10aS,10bR)-7-[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-ethenyldodecahydro-1,1,4a,7-tetramethyl-1H-cyclopropa[e]azulen-4(2H)-one; TBDMS Ether of a Steroid/Terpenoid Intermediate; tert-Butyldimethylsilyl (TBDMS) Protected Steroid Derivative; Complex Steroidal Ester with TBDMS and Pyranone Moieties; Advanced Synthetic Chiral Intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing specific results for assay, related substances, and other critical parameters are available upon request. We adhere to cGMP principles where applicable to support our clients' development and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed under an inert atmosphere if recommended to ensure long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.