Description

2-Methylpropenoic acid (1aR,5R,7S,10aS,10bR)-5-acetoxy-8-acetoxymethyl-1a,2,3,4,5,6,7,9,10a,10b-decahydro-1a,5-dimethyl-4,9-dioxooxireno[9,10]cyclodeca[1,2-b]furan-7-yl ester is a highly functionalized, complex organic ester derivative of methacrylic acid and a diterpenoid core. This compound is of significant interest for advanced organic synthesis and pharmaceutical research due to its intricate polycyclic structure and multiple reactive sites. It serves as a critical advanced intermediate for researchers and process chemists in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of complex, biologically active molecules and potential new chemical entities (NCEs).
• Advanced Organic Synthesis: Used in academic and industrial R&D for constructing complex molecular architectures, leveraging its multiple functional groups for selective transformations.
• Medicinal Chemistry Research: Serves as a precursor for creating analogs and derivatives for structure-activity relationship (SAR) studies in drug discovery programs.
• Fine Chemical Production: Intermediate in the multi-step synthesis of high-value specialty chemicals, including catalysts and ligands.
• Bioconjugation & Prodrug Development: The methacrylate moiety can be utilized for polymerizable derivatives or as a handle for creating prodrug formulations.

Basic Information

Product Name	2-Methylpropenoic acid (1aR,5R,7S,10aS,10bR)-5-acetoxy-8-acetoxymethyl-1a,2,3,4,5,6,7,9,10a,10b-decahydro-1a,5-dimethyl-4,9-dioxooxireno[9,10]cyclodeca[1,2-b]furan-7-yl ester
CAS No.	11091-29-5
Molecular Formula	C24H30O9
Molecular Weight	462.49 g/mol
Synonyms	7α-Methacryloyloxy-6β-acetoxyvouacapen-5α-ol; Vouacapen-5α-ol, 6β-acetoxy-7α-(2-methyl-1-oxo-2-propen-1-yloxy)-, (7α)-; Taxinine M 7-Methacrylate; 6β-Acetoxy-7α-methacryloyloxytaxinine M; A complex taxane derivative ester; 7-Methacryloyltaxinine M 6-acetate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

This high-purity research chemical is produced under strict quality control protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Our quality assurance includes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) is provided with each batch, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.