Description

(7E,13E,15E,17E,19E)-21-(4-amino-3,5-dihydroxy-6-methyl-oxan-2-yl)oxy-12-ethyl-1,3,5,25-tetrahydroxy-11-methyl-9-oxo-10,27-dioxabicyclo[21.3.1]heptacosa-7,13,15,17,19-pentaene-24-carboxylic acid is a complex macrolide compound of significant interest in advanced pharmaceutical research and development. Its intricate polyene and glycosylated structure makes it a valuable intermediate for the synthesis of novel bioactive molecules, particularly in the field of anti-infective and anti-cancer agents. This high-purity chemical is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing new therapeutic entities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel macrolide antibiotics and other complex therapeutic agents.
• Biochemical Research: Used in academic and industrial laboratories to study structure-activity relationships (SAR) of polyene macrolides.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: A key starting material for the semi-synthesis of derivatives with potential enhanced pharmacological profiles or reduced toxicity.
• API Development: Investigated as a precursor in the development pathway for new Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	(7E,13E,15E,17E,19E)-21-(4-amino-3,5-dihydroxy-6-methyl-oxan-2-yl)oxy-12-ethyl-1,3,5,25-tetrahydroxy-11-methyl-9-oxo-10,27-dioxabicyclo[21.3.1]heptacosa-7,13,15,17,19-pentaene-24-carboxylic acid
CAS No.	11076-50-9
Molecular Formula	C34H49NO13
Molecular Weight	679.76 g/mol
Synonyms	Amphotericin B; Amphotericin; Amphotericin B (USP); Fungizone; Ampho B; Amphotericin B1; 11076-50-9; Amphotericin B complex component
EINECS	234-298-1

Quality Control

Our Amphotericin B is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, identification by IR and NMR spectroscopy, and tests for specific impurities and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.