Description

4-Oxo-1-(2-Pyrimidinyl)-Cyclohexanecarbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused-ring structure containing both pyrimidine and cyclohexanone motifs. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors engaged in developing new small-molecule drugs and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides that leverage its heterocyclic core for biological activity.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for organic electronic materials and ligands in catalytic systems due to its electron-deficient pyrimidine ring.

Basic Information

Product Name	4-Oxo-1-(2-Pyrimidinyl)-Cyclohexanecarbonitrile
CAS No.	960371-41-9
Molecular Formula	C11H11N3O
Molecular Weight	201.23 g/mol
Synonyms	1-(Pyrimidin-2-yl)-4-oxocyclohexanecarbonitrile; 4-Oxo-1-(pyrimidin-2-yl)cyclohexane-1-carbonitrile; Cyclohexanecarbonitrile, 4-oxo-1-(2-pyrimidinyl)-; 960371-41-9; 4-Oxo-1-pyrimidin-2-yl-cyclohexanecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Oxo-1-(2-Pyrimidinyl)-Cyclohexanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.