Description

2-(2,5-Difluoro-Phenyl)-Pyrimidine-5-Carbonitrile is a high-purity fluorinated pyrimidine derivative, a key building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which is critical for introducing specific fluorinated aromatic and heterocyclic motifs into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a key scaffold in the development of new herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine atoms.
• Material Science: Used in the research and development of advanced organic electronic materials, such as OLEDs and semiconductors.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyclization reactions to construct complex heterocyclic systems.
• Life Science Research: Acts as a probe or a tagged compound in biochemical assays and diagnostic research due to its distinct chemical signature.

Basic Information

Product Name	2-(2,5-Difluoro-Phenyl)-Pyrimidine-5-Carbonitrile
CAS No.	960198-63-4
Molecular Formula	C11H5F2N3
Molecular Weight	217.18 g/mol
Synonyms	2-(2,5-Difluorophenyl)pyrimidine-5-carbonitrile; 5-Cyano-2-(2,5-difluorophenyl)pyrimidine; Pyrimidine-5-carbonitrile, 2-(2,5-difluorophenyl)-; 2-(2,5-Difluorophenyl)-5-pyrimidinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-(2,5-Difluoro-Phenyl)-Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.