Description

2-(3-Fluoro-Phenyl)-Pyrimidine-5-Carbonitrile is a high-purity fluorinated pyrimidine derivative, a key heterocyclic building block prized for its structural complexity and functional versatility. This compound matters significantly in modern chemical synthesis, serving as a critical intermediate for constructing advanced molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	2-(3-Fluoro-Phenyl)-Pyrimidine-5-Carbonitrile
CAS No.	960198-61-2
Molecular Formula	C11H6FN3
Molecular Weight	199.19 g/mol
Synonyms	2-(3-Fluorophenyl)pyrimidine-5-carbonitrile; 5-Cyano-2-(3-fluorophenyl)pyrimidine; 2-(3-Fluorophenyl)-5-pyrimidinecarbonitrile; 3-Fluoro-2-pyrimidin-5-ylbenzonitrile (incorrect but common misnomer); 960198-61-2; 2-(3-Fluorophenyl)pyrimidine-5-carbonitrile; 5-Pyrimidinecarbonitrile, 2-(3-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-(3-Fluoro-Phenyl)-Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.