Description

2-(4-Fluoro-Phenyl)-Pyrimidine-5-Carbonitrile is a high-purity fluorinated pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. Its value lies in its precise molecular architecture, which is essential for constructing complex molecules with targeted biological or material properties. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Building Block: Used in the creation of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient pyrimidine core.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the global life sciences market.
• Academic & Institutional Research: Used in university and government laboratories for fundamental research in medicinal chemistry and heterocyclic chemistry.

Basic Information

Product Name	2-(4-Fluoro-Phenyl)-Pyrimidine-5-Carbonitrile
CAS No.	960198-60-1
Molecular Formula	C11H6FN3
Molecular Weight	199.18 g/mol
Synonyms	5-Cyano-2-(4-fluorophenyl)pyrimidine; 2-(4-Fluorophenyl)-5-pyrimidinecarbonitrile; 4-Fluoro-2-pyrimidin-5-ylbenzonitrile; 960198-60-1; 2-(p-Fluorophenyl)pyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-Phenyl)-Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.