Description

2-(3,5-Difluoro-Phenyl)-Pyrimidine-5-Carboxylic Acid Amide is a high-purity, heterocyclic organic compound featuring a pyrimidine core substituted with a difluorophenyl group and a primary amide. This molecular structure makes it a valuable and versatile pharmaceutical intermediate and research chemical for the development of novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme function and biological pathways.
• Material Science: Potential monomer or additive for creating specialized polymers with unique electronic or thermal properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules.

Basic Information

Item	Details
Product Name	2-(3,5-Difluoro-Phenyl)-Pyrimidine-5-Carboxylic Acid Amide
CAS No.	960198-59-8
Molecular Formula	C11H7F2N3O
Molecular Weight	235.19 g/mol
Synonyms	2-(3,5-Difluorophenyl)pyrimidine-5-carboxamide; 5-Carbamoyl-2-(3,5-difluorophenyl)pyrimidine; 2-(3,5-Difluorophenyl)-5-pyrimidinecarboxamide; 960198-59-8; Amide, 2-(3,5-difluorophenyl)-5-pyrimidinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(3,5-Difluoro-Phenyl)-Pyrimidine-5-Carboxylic Acid Amide is manufactured under a cGMP-compliant quality management system (where applicable) and undergoes rigorous analytical testing. Our products are guaranteed to meet the high-purity standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.