Description

2-(2-Fluoro-Phenyl)-Pyrimidine-5-Carboxylic Acid Amide is a high-purity fluorinated pyrimidine derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific fluorine-substituted aromatic system imparts desirable biological activity and metabolic stability. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy and environmental profile.
• Material Science Research: Serves as a precursor for the synthesis of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Employed as a molecular scaffold or a tagging reagent in the design of chemical probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	2-(2-Fluoro-Phenyl)-Pyrimidine-5-Carboxylic Acid Amide
CAS No.	960198-57-6
Molecular Formula	C11H8FN3O
Molecular Weight	217.20 g/mol
Synonyms	2-(2-Fluorophenyl)pyrimidine-5-carboxamide; 2-(2-Fluorophenyl)-5-pyrimidinecarboxamide; 5-Carbamoyl-2-(2-fluorophenyl)pyrimidine; 2-(2-Fluorophenyl)pyrimidine-5-carboxylic acid amide; 960198-57-6; Amide, 2-(2-fluorophenyl)-5-pyrimidinecarboxylic; 2-(2-Fluorophenyl)-5-pyrimidinecarboxylic acid amide
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-Phenyl)-Pyrimidine-5-Carboxylic Acid Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with various pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.