Description

2-(3-Fluoro-Phenyl)-Pyrimidine-5-Carboxylic Acid Amide is a high-purity fluorinated pyrimidine derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific fluorine-substituted aromatic core is critical for modulating biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce novel fluorinated heterocyclic scaffolds into their molecular targets.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorophenyl-pyrimidine moiety enhances efficacy and environmental profile.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-(3-Fluoro-Phenyl)-Pyrimidine-5-Carboxylic Acid Amide
CAS No.	960198-56-5
Molecular Formula	C11H8FN3O
Molecular Weight	217.20 g/mol
Synonyms	2-(3-Fluorophenyl)pyrimidine-5-carboxamide; 5-Carbamoyl-2-(3-fluorophenyl)pyrimidine; 2-(3-Fluorophenyl)-5-pyrimidinecarboxamide; 960198-56-5; Amide, 2-(3-fluorophenyl)-5-pyrimidinecarboxylic; 2-(3-FLUORO-PHENYL)-PYRIMIDINE-5-CARBOXYLIC ACID AMIDE
EINECS	Contact for details

Quality Control

Our 2-(3-Fluoro-Phenyl)-Pyrimidine-5-Carboxylic Acid Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical and agrochemical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.