Description

2-(3,5-Diluorophenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester is a high-value fluorinated pyrimidine derivative, a critical building block in modern organic synthesis. Its precise molecular architecture, featuring a difluorophenyl group and a pyrimidine ester, makes it an essential intermediate for creating complex, bioactive molecules. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for constructing specialized ligands used in catalysis and material science.
• Organic Electronics Research: Investigated as a building block for electron-deficient units in organic semiconductors and light-emitting materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for custom synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	2-(3,5-Diluorophenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester
CAS No.	960198-54-3
Molecular Formula	C12H8F2N2O2
Molecular Weight	250.20 g/mol
Synonyms	Methyl 2-(3,5-difluorophenyl)pyrimidine-5-carboxylate; 2-(3,5-Difluorophenyl)-5-pyrimidinecarboxylic acid methyl ester; 960198-54-3; 2-(3,5-Difluorophenyl)pyrimidine-5-carboxylic acid methyl ester; Methyl 2-(3,5-difluorophenyl)-5-pyrimidinecarboxylate; 5-(Methoxycarbonyl)-2-(3,5-difluorophenyl)pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-(3,5-Diluorophenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA), including HPLC purity, identity confirmation (NMR, MS), and impurity profile, is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.